Week 3

Unnatural Peptide Design and Multivalent Antibodies

Submitted by stephen on Wed, 05/05/2010 - 06:45
Semester: 
Week 3
The title of this weeks seminar was Unnatural Peptide Design and Multivalent Antibodies.  The speaker was Basar Bilgicer, an Assistant Professor at the University of Notre Dame.  He received his BS degree in chemistry from Bogazici University in Turkey and his PhD in Chemistry at Tufts University in Boston.  During his graduate studies he published several first author articles in the top tier journals in his field.  He was a good speaker and enthusiastic about the material. I learned about the two types of antibodies, monovalent and bivalent.  I learned that antibodies do not always bind to

Multivalent Antibody Aggregation

Submitted by choig on Thu, 02/18/2010 - 02:40
Semester: 
Week 3

The chemistry seminar that was held on January 28, 2010 was titled “Peptide Design Using Unnatural Amino Acids & Multivalent Antibody Aggregation,” and the speaker was Basar Bilgicer. However, he only presented about multivalent antibody aggregation. Basar Bilgicer was born in Istanbul and received a bachelor’s degree in chemistry at Bogazici University, Turkey. Following that, he received a Ph.D. at Tuff University.

Peptide Design Using Unnatural Amino Acids and Multivalent Antibody Aggregation by Basar Bilgicer

Submitted by seonui on Sun, 02/07/2010 - 20:53
Semester: 
Week 3

The guest speaker of the chemistry seminar held on January 28 was Basar Bilgicer, who is an assistant professor in the Department of Chemical & Biomolecular Engineering at University of Notre Dame. During the presentation, he focused on antibodies, such as IgG, and their aggregations to form multivalent molecules in biological systems and friendly explained about them. I think his seminar really helped students get a deeper understanding of antibody aggregation.

Multivalent Antibody Aggregation

Submitted by young on Sun, 02/07/2010 - 20:49
Semester: 
Week 3

On January 28, 2010, Basar Bilgicer who is a professor at University of Notre Dame visited Andrews University for his presentation. Mr. Basar Bilgicer prepared two presentations. One of them was “Peptide Design Using Unnatural Amino Acids.” The other was “Multivalent Antibody Aggregation.”  More students in the presentation wanted to know about the antibody aggregation. Therefore, he started the presentation, introducing us the basis of antibody. Especially, he talked about IgG antigen.

Unnatural Peptide Design & multivalent Antibodies

Submitted by chem nerd on Sun, 02/07/2010 - 17:58
Semester: 
Week 3

On January 25th our chem seminar speaker traveled ALL the way from South Bend, IN to give us a very informative lecture on how unnatural amino acids & multivalent antibody aggregation is crucial to science research. Our presenter was Başar Bilgiçer, assistant professor in both the Chemical and Bimolecular Engineering Department and the Chemistry and Biochemistry Department at the University of Notre Dame. He completed his B.S. in Chemistry at Bogazici University, Turkey; he then went on to receive his Ph.D.

Peptide Design Using Unnatural Amino Acids and Multivalent Antibodies

Submitted by Troy on Wed, 02/03/2010 - 16:05
Semester: 
Week 3

This week in Chemistry Seminar we enjoyed a presentation from Dr. Basar Bilgicer on the aggregation of antibodies and their "antigens" with each other. First of all, a quick recap on antibodies, what they are, what they are used for, and why they are so critical. Antibodies are proteins produced by cells of the immune system and, when bound to their specific antigen (toxin, carcinogen, etc.) will elicit an immune response to increase the number of antibodies in the blood.

Multivalent Antibody Aggregation

Submitted by Danuel Brown on Wed, 02/03/2010 - 02:41
Semester: 
Week 3

This week’s speaker was Basar Bilgicer, who presented on multivalent antibodies.  He stated that one of the major challenges for antibodies is to be found by the appropriate pathogen in order to get rid of the pathogen.  There are a few different types of antibodies.  There are monovalent and bivalent antibodies in the body, a monovalent antibody is like the antibody grabbing on to the pathogen with one arm.  Whereas a bivalent antibody would be like grabbing on with two arms.

Multivalent Antibodies and their benefits

Submitted by shulla on Sun, 01/31/2010 - 18:40
Semester: 
Week 3

Dr. Basar Bilgicer was the featured presenter at this week's ChemSem installment. The simple focus of his presentation worked upon the well known chemical fact that two bonds are better than one. A complex organism produces antibodies which, upon encountering a foreign antigen, attach to its surface. When a large number of these antibodies attach, the mass and concentration triggers and immune response which works to expel the antigen from the system now that it has been identified.

Peptide design using unnatural amino acids & multivalent antibody aggregation

Submitted by jongho on Sun, 01/31/2010 - 15:01
Semester: 
Week 3

Assistant chemical & biomolecular engineering professor from Notre Dame, Basar Bilgicer obviously was well qualified to do the presentation on amino acids and antibody, as he has worked on peptide design using unnatural amino acids while pursuing his PhD degree. His presentation was well-paced, ending right around the time when the seminar is supposed to be over, but over my head mostly, because I forgot a lot of things I learned in biology and biochemistry classes. However, the general idea of the presentation was easy to follow and understandable.

Multivalent Antibody Aggregation

Submitted by brummett on Sun, 01/31/2010 - 14:56
Semester: 
Week 3

For this seminars topic the presenter, Basar Bilgicer, allowed the audience to choose the topic that they would like to here him present on.  The topic of choice was Multivalent Antibody Aggregation.  However, before we get into his talk here is a little background on our presenter.  Basar Bilgicer was born in Istanbul and received his undergraduate degree in Chemistry at Bogaziki University in Turkey.  In 1999 he found himself in Boston pursuing his PhD in Chemistry at Tufts University, where he worked on peptide design using unnatural amino acids.

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